Crohn's Disease
SEROVERA® can help control symptoms, maintain remission, and prevent relapse.
Whether you have been diagnosed or have had Crohn’s disease for years, it’s important to understand it's [Crohn's disease] on your life. It's also equally important to find the right treatment - as Crohn's disease left untreated, can lead to complications such as abcesses, perforations and fistulas, not to mention fatique and anemia.
SEROVERA® is a 100% natural, potent anti-inflammatory, PROVEN to heal crohn’s disease. Most people who take SEROVERA® testify to significant health improvement from their crohn’s disease within a few weeks.
Under the direction of Dr. Ivan Danhof, Ph.D., M.D., we have isolated and processed the aloe mucilaginous polysaccharide healing agent in Aloe Vera, allowing us to infuse the purest, most potent medicinal value into each SEROVERA® AMP 500 capsule.
For more information, visit SEROVERA.com today.
What is Crohn's Disease
Crohn's disease is a condition that causes inflammation of the wall of the gut. Any part of the gut can be affected. This can lead to various symptoms (detailed below). Crohn's disease is named after Dr Crohn, the person who first described the disease in the 1930s.
Understanding The Gut
The gut (gastrointestinal tract) is the long tube that starts at the mouth and ends at the anus. When we eat, food passes down the esophagus (gullet), into the stomach, and then into the small intestine.
The small intestine has three sections - the duodenum, jejunum and ileum. The small intestine is where food is digested and absorbed into the bloodstream. The structure of the gut then changes to become the large intestine (colon and rectum, sometimes called the large bowel).
The colon absorbs water, and contains food that has not been digested, such as fiber. This is passed into the last part of the large intestine, where it is stored as feces. Feces (motions or stools) are then passed out of the anus into the toilet
Who gets Crohn's disease?
Crohn's disease affects about 1 in 10,000 people. If you have a family member with Crohn's disease you are more likely to develop the condition yourself. It is also more common in people who have had their appendix removed, for the first five years after the operation.
Which part of the gut is affected in Crohn's disease?
In Crohn's disease, one or more patches of inflammation develop in parts of the gut. Any part of the gut can be affected. However, the most common site for the disease first to start is the last part of the small intestine (the ileum). The ileum is affected in about half of cases. Other parts of the small intestine and the colon are also commonly affected. The mouth, gullet and stomach are affected much less commonly.
A patch of inflammation may be small, or spread quite a distance along part of the gut. Several patches of inflammation may develop along the gut, with normal sections of gut in between. In about 3 in 10 cases, the inflammation occurs just in the small intestine. In about 2 in 10 cases the inflammation occurs just in the colon. In a number of cases, the inflammation occurs in different places in the gut.
What causes Crohn's disease?
The cause is not known. About 3 in 20 people with Crohn's disease have a close relative who also has it. This means there may be some genetic factor. However, other factors such as a bacterium or virus (germ) may be involved. One theory is that a germ may trigger the immune system to cause inflammation in parts of the gut in people who are genetically prone to developing the disease.
Crohn's disease has become more common in recent years, but the reason for this is not known. It is about twice as common than average in smokers. Also, on average, smokers tend to have more severe disease than non-smokers. The oral contraceptive pill and non-steroidal anti-inflammatory tablets (usually used for joint inflammation) have also been implicated as possible causes or triggers.
What are the symptoms during a flare-up of Crohn's disease?
Symptoms are due to inflammation in the wall of the affected parts of the gut. When the disease flares up, the inflammation may cause one or more of the following:
- Diarrhea is the most common first symptom. It can vary from mild to severe. The diarrhea may be mixed with mucus, pus or blood. An urgency to get to the toilet is common. A feeling of wanting to go to the toilet but with nothing to pass is also common (tenesmus).
- Pain occurs in about 7 in 10 cases. The site of the pain depends on which part of the gut is affected. The last part of the small intestine (ileum) is the most common site. Therefore, a common area of pain is the lower right side of the abdomen. When Crohn's disease first develops it is sometimes mistaken for appendicitis. The severity of pain can vary from person to person. Also, a sudden change or worsening of pain may indicate a complication (see below).
- Weight loss that is not intentional is another common symptom.
- Ulcers. An ulcer is a raw area of the lining of the gut which may bleed. You may see blood when you pass stools (motions or feces).
- Generally feeling unwell which may include loss of appetite, fever, and tiredness?
- Anemia may occur if you lose a lot of blood.
- Mouth ulcers are common.
- Anal fissures may occur. These are painful cracks in the skin of the anus. Skin tags (small fleshy wart-like lumps) may also appear around the anus.
Symptoms can vary and depend on which part or parts of the gut are affected. For example:
- You may not have diarrhea if the disease is just in the small intestine.
- A persistent pain in the abdomen without any other symptoms may be due to a small patch of Crohn's disease in the small intestine.
- A severe flare-up can make you generally very ill.
- If large parts of the gut are affected, you may not absorb food well, and you may become deficient in vitamins and other nutrients.
Other symptoms
Other parts of the body are affected in some people in addition to the gut. These include: inflammation and pain of some joints (arthritis); skin rashes; inflammation of the eye (uveitis); liver inflammation. These problems can cause various symptoms.
It is not clear why these other problems occur. The immune system may trigger inflammation in other parts of the body when there is inflammation in the gut. These other problems tend to go when the gut symptoms settle, but not always.
How does Crohn's disease progress?
Crohn's disease is a chronic, relapsing condition. Chronic means that it is ongoing. Relapsing means that there are times when symptoms flare up (relapse), and times when there are few or no symptoms (remission). The severity of symptoms, and how frequently they occur, varies from person to person. The first episode (flare-up) of symptoms is often the worst.
What are the treatment options for a flare-up of Crohn's disease?
The treatment advised can depend on various factors. For example, the severity of the symptoms, the site or sites of the inflammation in the gut, whether associated problems have developed and what treatments worked best for you in the past. Treatment decisions can become complex.
If you have Crohn's and have tried other therapies without success, SEROVERA® may help get real control over your Crohn's symptoms.
SEROVERA® helps remit Crohn's and relieve symptoms by stamping-out the inflammation process. Many individuals have achieved positive response in as little as two weeks and continue to progress through ongoign therapy with SEROVERA®.
For more information, visit SEROVERA.com today.
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